BDBM50084135 3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL151416

SMILES C[C@H]1CN(Cc2ccccc2)CCN1C(c1ccc(cc1)C(C)(C)C)c1cccc(O)c1

InChI Key InChIKey=AHXMJVFHPCQZOY-XYXHBKGXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084135   

TargetMu-type opioid receptor(MOUSE)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Affinity DataIC50:  290nMAssay Description:Agonist activity of the compound was determined using electrically induced smooth muscle contraction of mouse vas deferens.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of [3H]-DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 using rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084135(3-[((S)-4-Benzyl-2-methyl-piperazin-1-yl)-(4-tert-...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of [3H]-deltorphin binding to Opioid receptor delta 1 using rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed