BDBM50084150 CHEMBL3425951
SMILES CN(C)CCC(=O)Nc1cncc(c1)-c1cccc2[nH]ccc12
InChI Key InChIKey=PQZUAOABAJEGLH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50084150
Affinity DataIC50: 460nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair