BDBM50084152 CHEMBL3425949
SMILES CC(C)(O)c1nc(no1)-c1ccc(CNC(=O)c2cnc(nc2)-c2ccccn2)cc1
InChI Key InChIKey=DVKUIAJDBLWGMN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50084152
Affinity DataIC50: 70nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair