BDBM50084304 (4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid::CHEMBL44898

SMILES OC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1

InChI Key InChIKey=YWAPUIQWVUXRRW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084304   

TargetMatrilysin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  7.70E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  6.70E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084304((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...)
Affinity DataIC50:  5.00E+4nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed