BDBM50084423 CHEMBL3426706

SMILES O[C@@H](CNCCc1cccc(NC(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2-c2ccccc2)c1)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=DUQNZGIGZOEZHH-BHVANESWSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084423   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50084423(CHEMBL3426706)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Theravance Biopharma

Curated by ChEMBL
LigandPNGBDBM50084423(CHEMBL3426706)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed