BDBM50084504 CHEMBL3426991
SMILES Nc1cccc(c1)-c1ccc2c(cc(Nc3ccccc3)[nH]c2=O)c1
InChI Key InChIKey=OURCBWJERHUWHH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50084504
Affinity DataKi: 1.90E+3nMAssay Description:Competitive inhibition of His6-tagged human recombinant Cdc25B catalytic domain (350 to 566 residues) expressed in Escherichia coli BL21 (D3) after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of Cdc25B-mediated entry in to mitosis in etoposide-treated human U2OS cells incubated for 16 hrs in presence of nocodazole by Hoechst 333...More data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of His6-tagged human recombinant Cdc25B catalytic domain (350 to 566 residues) expressed in Escherichia coli BL21 (D3) using OMFP substrat...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using OMFP substrate after 20 mins by spectrophotometryMore data for this Ligand-Target Pair