BDBM50084650 CHEMBL177914::{(S)-1-[(S)-1-Formyl-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester::{1-[1-Formyl-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester(Cbz-Phe-Tyr-CHO)

SMILES Oc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)C=O)cc1

InChI Key InChIKey=QVDJMLQSYRSZKC-UPVQGACJSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084650   

TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.260nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.470nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataKi:  0.740nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataIC50:  85.1nMAssay Description:Inhibitory activity against Cathepsin BChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataIC50:  184nMAssay Description:Inhibitory activity against Calpain 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against cathepsin L, lysosomal cysteine proteaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed