BDBM50084737 4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::4-benzoyl-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamide::CHEMBL421644

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1ccccc1

InChI Key InChIKey=XSGJDCITTFQFMZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50084737   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  81nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  1.52E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcilysin(Plasmodium falciparum (isolate 3D7))
California State University

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum 3D7 FLN (55 to 1193 residues) expressed in Escherichia coli BL21 using Dabcyl-HKRHSFRMRG-EDANS as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  66.0nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084737(4-Benzoyl-1-(4-methoxy-benzenesulfonyl)-piperazine...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed