BDBM50084738 4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL126044

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(=O)(=O)c1sc(N)nc1C

InChI Key InChIKey=HWRVCRDVLWYPOY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084738   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  2.10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  1.28E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084738(4-(2-Amino-4-methyl-thiazole-5-sulfonyl)-1-(4-meth...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed