BDBM50084849 Bis-quinolinium cyclophane analogue::CHEMBL258254::Cyclo(N-decane1-{4-[2-[4-(4-amino-1-quinoliniumylmethyl)phenyl]-(Z)-1-ethenyl]benzyl}-4-quinoliniumamine)

SMILES C1CCCCCN[c+]2ccn(Cc3ccc(cc3)\C=C/c3ccc(Cn4cc[c+](NCCCC1)c1ccccc41)cc3)c1ccccc21

InChI Key InChIKey=XDWIBNDNEBICCV-ZCXUNETKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084849   

TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084849(Bis-quinolinium cyclophane analogue | CHEMBL258254...)
Affinity DataIC50:  150nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084849(Bis-quinolinium cyclophane analogue | CHEMBL258254...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article