BDBM50084851 Bis-quinolinium cyclophane analogue::CHEMBL266885::Cyclo N-decane(1-{4-[4-(4-amino-1-quinoliniumylmethyl)phenethyl]benzyl}-4-quinoliniumamine)

SMILES C1CCCCCN[c+]2ccn(Cc3ccc(CCc4ccc(Cn5cc[c+](NCCCC1)c1ccccc51)cc4)cc3)c1ccccc21

InChI Key InChIKey=YBUJEFDKDCEBNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084851   

TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50084851(Bis-quinolinium cyclophane analogue | CHEMBL266885...)
Affinity DataIC50:  180nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50084851(Bis-quinolinium cyclophane analogue | CHEMBL266885...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration of compound required for SKCa blocking action was assessed from its ability to inhibit After hyperpolarisation (AHP) in cult...More data for this Ligand-Target Pair
In DepthDetails Article