BDBM50084959 11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo-[2,3-f]indole-3,4'-piperidine](SB-224289)::4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl-1'-methylspiro[3,5,6,7-tetrahydro-2H-furo[2,3-f]indole-3,4'-(hexahydropyridine)]-5-ylmethanone::CHEMBL281350::SB-224289::[2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-yl]-[3-(1-methyl-piperidine)-2,3,6,7-tetrahydro-1-oxa-5-aza-s-indacen-5-yl]-methanone

SMILES CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1

InChI Key InChIKey=ATQMRMGXINTJHV-UHFFFAOYSA-N

Data  39 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50084959   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  6.31nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  501nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  631nMAssay Description:Compound was tested for binding affinity against human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Sus scrofa)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against piglet hippocampus 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against Alpha-1A adrenergic receptor (rat submaxillary gland)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against Alpha-1B adrenergic receptor (rat liver ,[3H] prazosin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against Histamine H1 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity towards Histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(MOUSE)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against Alpha-2B adrenergic receptor (NG 108-15 cells) using [3H]RX-821002) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity against human cloned Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  1.58E+3nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >3.16E+3nMAssay Description:Compound was tested for binding affinity against human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity against human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity against human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed