BDBM50085509 CHEMBL104995::Cyclic urea 2,4-diazepin-3-one analogue

SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(CC2)S(=O)(=O)c2cccs2)C1=O

InChI Key InChIKey=WDNGKOMGWMGLJU-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085509   

TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  12nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  52nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed