BDBM50085514 3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-[1,3]diazepan-1-yl]-benzamidine; Trifluoroacetate::CHEMBL102345

SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3cccs3)CC2)C1=O

InChI Key InChIKey=ZQBIZNIEVSXBPJ-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085514   

TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  80nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed