BDBM50085521 CHEMBL553840::Cyclic urea 2,4-diazepin-3-one analogue

SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=IVFAJJALDLLBIV-UHFFFAOYSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085521   

TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  102nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  282nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed