BDBM50086604 CHEMBL3426308
SMILES [H][C@@]12C[C@]1(C)Cc1[nH]nc(C(=O)Nc3cnn(c3)[C@@H](C3CCS(=O)(=O)CC3)c3ccccc3)c1C2
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50086604
Affinity DataKi: 0.200nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of ITK in TCR stimulated human Jurkat T cells assessed as reduction of PLC-gamma phosphorylation preincubated for 30 mins followed by TCR ...More data for this Ligand-Target Pair