BDBM50086613 CHEMBL138999::Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-(pyridin-2-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium;
SMILES Cc1cc(C)cc(c1)-c1c(OCCC2CCCC[NH2+]2)c2cc(C(=O)Nc3ccccn3)c(Cl)cc2[nH]c1=O
InChI Key InChIKey=INFUSDDIQHZLPP-UHFFFAOYSA-O
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50086613
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:In vitro inhibition of GnRH stimulated release of luteinizing hormone from the rat primary pituitary cells.More data for this Ligand-Target Pair