BDBM50086673 8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1,4]thiazin-3-one::CHEMBL140908

SMILES CC(C)(C)NCC(O)COc1cccc2NC(=O)CSc12

InChI Key InChIKey=SWWQDUZAPYPHEI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086673   

TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50086673(8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its Beta-1 adrenergic receptor binding affinity by measuring the displacement of [3H]-dihydroalprenolol binding in rat hea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Università

Curated by ChEMBL
LigandPNGBDBM50086673(8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1...)
Affinity DataKi:  23nMAssay Description:Beta-2 adrenergic receptor binding affinity by measuring the displacement of [3H]-DHA binding in rat lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50086673(8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1...)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 adrenergic receptor binding affinity by measuring the displacement of [3H]-prazosin binding in rat brain; Not Active means Ki >1000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50086673(8-(3-tert-Butylamino-2-hydroxy-propoxy)-4H-benzo[1...)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-2 adrenergic receptor binding affinity by measuring the displacement of [3H]clonidine binding in rat cerebral cortex; Not Active means Ki >1000...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed