BDBM50086897 CHEMBL24213::[4-(2-Benzyl-benzo[b]thiophen-3-yl)-[1,1'';3'',1'''']terphenyl-4''-yloxy]-acetic acid::[4-(2-Benzyl-benzo[b]thiophen-3-yl)-[1,1':3',1'']terphenyl-4'-yloxy]-acetic acid::[4-(2-Benzyl-benzo[b]thiophen-3-yl)-[1,1';3',1'']terphenyl-4'-yloxy]-acetic acid

SMILES OC(=O)COc1ccc(cc1-c1ccccc1)-c1ccc(cc1)-c1c(Cc2ccccc2)sc2ccccc12

InChI Key InChIKey=DUKPJMRESMYJTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50086897   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086897(CHEMBL24213 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086897(CHEMBL24213 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)-...)
Affinity DataIC50:  4.89E+7nMAssay Description:Inhibitory activity determined against Protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086897(CHEMBL24213 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)-...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086897(CHEMBL24213 | [4-(2-Benzyl-benzo[b]thiophen-3-yl)-...)
Affinity DataIC50:  9.99E+7nMAssay Description:Concentration required for 50% inhibition of tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed