BDBM50086950 2-[4-[4-(2-benzylbenzo[b]thiophen-3-yl)phenyl]-2,6-di(4-methoxyphenyl)phenoxy]acetic acid::2-{4-[4-(2-benzyl-1-benzothiophen-3-yl)phenyl]-2,6-bis(4-methoxyphenyl)phenoxy}acetic acid::CHEMBL284471::[4'-(2-Benzyl-benzo[b]thiophen-3-yl)-biphenyl-4-yloxy, 3,5 {bis-(4-methoxy-phenyl)}]-acetic acid

SMILES COc1ccc(cc1)-c1cc(cc(-c2ccc(OC)cc2)c1OCC(O)=O)-c1ccc(cc1)-c1c(Cc2ccccc2)sc2ccccc12

InChI Key InChIKey=MXPGUEIHEJPIBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086950   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086950(2-[4-[4-(2-benzylbenzo[b]thiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086950(2-[4-[4-(2-benzylbenzo[b]thiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50:  25.1nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50086950(2-[4-[4-(2-benzylbenzo[b]thiophen-3-yl)phenyl]-2,6...)
Affinity DataIC50:  2.51E+7nMAssay Description:Concentration required for 50% inhibition of tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed