BDBM50088070 CHEMBL301977::{5-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-2-methoxy-phenyl}-carbamic acid tert-butyl ester

SMILES COc1ccc(cc1NC(=O)OC(C)(C)C)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=ATNNMKHWMHMLHP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088070   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088070(CHEMBL301977 | {5-[Hydroxycarbamoylmethyl-(4-nitro...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088070(CHEMBL301977 | {5-[Hydroxycarbamoylmethyl-(4-nitro...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088070(CHEMBL301977 | {5-[Hydroxycarbamoylmethyl-(4-nitro...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088070(CHEMBL301977 | {5-[Hydroxycarbamoylmethyl-(4-nitro...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088070(CHEMBL301977 | {5-[Hydroxycarbamoylmethyl-(4-nitro...)
Affinity DataKi:  25nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed