BDBM50088095 2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N-hydroxyacetamide::CHEMBL293774::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(4-nitro-benzyl)-amino]-acetamide

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=LOYIGNDQOZNJNZ-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50088095   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  18nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataKi:  31nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088095(2-(N-(4-nitrobenzyl)-4-methoxyphenylsulfonamido)-N...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed