BDBM50088102 CHEMBL53009::[(4-Nitro-benzyl)-(3-(N-benzene sulfonyl)-ureido-benzenesulfonyl)-amino]-acetic acid

SMILES OC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=RTBPRRSADWSXAD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088102   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088102(CHEMBL53009 | [(4-Nitro-benzyl)-(3-(N-benzene sulf...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088102(CHEMBL53009 | [(4-Nitro-benzyl)-(3-(N-benzene sulf...)
Affinity DataKi:  22nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088102(CHEMBL53009 | [(4-Nitro-benzyl)-(3-(N-benzene sulf...)
Affinity DataKi:  27nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088102(CHEMBL53009 | [(4-Nitro-benzyl)-(3-(N-benzene sulf...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088102(CHEMBL53009 | [(4-Nitro-benzyl)-(3-(N-benzene sulf...)
Affinity DataKi: >100nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed