BDBM50088222 (2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pentanedioic acid::CHEMBL301536::E-2-Amino-4-(3-naphthalen-2-yl-allyl)-pentanedioic acid(LY339434)::LY-339434
SMILES N[C@@H](C[C@@H](C\C=C\c1ccc2ccccc2c1)C(O)=O)C(O)=O
InChI Key InChIKey=KNAYYBRIBNEIAL-WNEUIUNWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50088222
Affinity DataKi: 14nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-AMPA as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound was determined against Glutamate receptor (KA2) using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 4 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Ability of the compound to bind to Ionotropic glutamate receptor kainate (kainate 2) was evaluated.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 4 in HEK293 cells using [3H]-AMPA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 1 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.37E+4nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-kainate as radiol...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+4nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 2 in HK293 cells using [3H]-kainate as radiol...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against human GluR6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+5nMAssay Description:Agonist activity at GluA1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at GluK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at GluK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Compound was tested for agonistic activity on rat dorsal root ganglion neurons (thought to express GluR5 receptors)More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 6 using HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Effective concentration against GluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair