BDBM50088825 CHEMBL353422::Sodium; 3-((E)-2-nitro-vinyl)-5,5,8-trioxo-7-[1-pyridin-2-yl-meth-(Z)-ylidene]-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

SMILES [O-]C(=O)C1=C(CS(=O)(=O)C2N1C(=O)\C2=C\c1ccccn1)\C=C\[N+]([O-])=O

InChI Key InChIKey=CPUGVYYSHKTHTN-JWVBWWOWSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088825   

TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  100nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  20nMAssay Description:The compound was evaluated for inhibition against the GC1 extended spectrum Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  70nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  200nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed