BDBM50088909 (4-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)methanol::CHEMBL367442::[4-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-phenyl]-methanol
SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)-c1ccc(CO)cc1
InChI Key InChIKey=QEKCMFKWDZHOOD-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50088909
Affinity DataIC50: 70nMAssay Description:Tested for inhibition of EGF-receptor tyrosine kinase in intact cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Tested in vitro for inhibition of EGF-receptor tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Tested for inhibition of protein tyrosine kinase c-Src phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Tested in vitro for inhibition of serine/threonine kinase Cdc2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Tested in vitro for inhibition of KDR-receptor tyrosine kinaseMore data for this Ligand-Target Pair