BDBM50089248 CHEMBL3577881

SMILES C[C@@H](N(Cc1cccc(c1)C(O)=O)C(=O)c1cc2ccccn2n1)c1ccc(F)cc1

InChI Key InChIKey=JIPVIQLALIVIQU-MRXNPFEDSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089248   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50089248(CHEMBL3577881)Copy SMILESCopy InChI

Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50089248(CHEMBL3577881)Copy SMILESCopy InChI

Affinity DataIC50:  94nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI