BDBM50089256 CHEMBL3577905

SMILES CC[C@@H](N(Cc1cccc(c1)C(O)=O)C(=O)c1cc2ccccn2n1)c1ccc(F)cc1F

InChI Key InChIKey=LWTRPOBSYVDNTC-HSZRJFAPSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089256   

TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50089256(CHEMBL3577905)Copy SMILESCopy InChI

Affinity DataIC50:  123nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI