BDBM50089513 (S)-7-Fluoro-3-(4-fluoro-phenyl)-8-methyl-2-propyl-8-aza-bicyclo[3.2.1]octane::CHEMBL33280

SMILES CCCC1C2[C@@H](F)CC(CC1c1ccc(F)cc1)N2C

InChI Key InChIKey=IADBQJBYXQKMJN-KLZNEWFBSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089513   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50089513((S)-7-Fluoro-3-(4-fluoro-phenyl)-8-methyl-2-propyl...)
Affinity DataKi:  30nMAssay Description:ability to displace [3H]- Mazindol binding to cocaine binding sites on Dopamine transporter of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50089513((S)-7-Fluoro-3-(4-fluoro-phenyl)-8-methyl-2-propyl...)
Affinity DataKi:  49nMAssay Description:Compound was tested for its ability to inhibit high affinity uptake of [3H]DA into rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50089513((S)-7-Fluoro-3-(4-fluoro-phenyl)-8-methyl-2-propyl...)
Affinity DataKi:  52nMAssay Description:Compound was tested for its ability to inhibit high-affinity uptake of [3H]NE into parietal and occipital cortex in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50089513((S)-7-Fluoro-3-(4-fluoro-phenyl)-8-methyl-2-propyl...)
Affinity DataKi:  561nMAssay Description:Compound was tested for its ability to inhibit high affinity uptake of [3H]5-HT into mid brain nerve endings (synaptosomes) in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed