BDBM50090041 6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propylcarbamoyl}-3,4-dimethyl-2-oxo-3,6-dihydro-2H-pyrimidine-1-carboxylic acid methyl ester::CHEMBL93623

SMILES COC(=O)N1[C@@H](C(C(=O)NCCCN2CCC(CC2)c2ccc(F)cc2)=C(C)N(C)C1=O)c1ccc(F)c(F)c1

InChI Key InChIKey=GPVSQYKLAUEUBR-AREMUKBSSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090041   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090041(6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-...)
Affinity DataKi:  0.75nMAssay Description:Evaluated for the ability to displace [125I]- HEAT from human cloned Alpha-1A adrenergic receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090041(6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-...)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090041(6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-...)
Affinity DataKi:  25nMAssay Description:Evaluated for the ability to displace [125I]- HEAT from human cloned Alpha-1B adrenergic receptor stably expressed in LM cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090041(6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-...)
Affinity DataKi:  170nMAssay Description:Evaluated for the ability to displace [125I]- HEAT from human cloned Alpha-1D adrenergic receptor stably expressed in HEK cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed