BDBM50090305 CHEMBL41994::N-[3-(4-Cyano-4-o-tolyl-piperidin-1-yl)-propyl]-2-(3,4-difluoro-phenyl)-3-methyl-butyramide

SMILES CC(C)C(C(=O)NCCCN1CCC(CC1)(C#N)c1ccccc1C)c1ccc(F)c(F)c1

InChI Key InChIKey=HTUPLSKAYCKZRG-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50090305   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of binding of [125I]HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090305(CHEMBL41994 | N-[3-(4-Cyano-4-o-tolyl-piperidin-1-...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed