BDBM50090694 CHEMBL3581740::US9259422, 22, R = Ph-BU128::US9480684, 22, R = Ph- BU128
SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@]51C[C@](C)([C@H](O)c4ccccc4)[C@]2(OC)C=C1)ccc3O
InChI Key InChIKey=AEIAQTQSFDKUPO-SRMCDNDASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50090694
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nM ΔG°: -13.8kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nM ΔG°: -13.8kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nM ΔG°: -12.7kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 97nM ΔG°: -9.56kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in HEK293 cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 97nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataEC50: 416nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cell membranes assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair