BDBM50091318 CHEMBL3582209
SMILES FC1CCN(Cc2ccc(cc2)-c2cnc3[nH]c4cnc(cc4c3c2)C#N)CC1
InChI Key InChIKey=MMWCIQZXVOZEGG-KSNRQLIKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50091318
Affinity DataEC50: 96nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair