BDBM50091349 CHEMBL3582271

SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12

InChI Key InChIKey=MGYNRIYGDOFIPG-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50091349   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1A adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1B adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1B adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1A adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed