BDBM50091474 (2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioic acid::CHEMBL299180::LY-339637

SMILES CC(C)\C=C(/C[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=AYWSXMRAQKWRMH-ZAXDUSRUSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50091474   

TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  54nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  518nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  700nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 1 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  3.70E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  5.60E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 4 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity of compound was determined against KA2 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091474((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Affinity DataKi:  8.25E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed