BDBM50091534 4-tert-Butyl-N-(5-methyl-4-methylsulfanyl-isoxazol-3-yl)-benzenesulfonamide::CHEMBL417595

SMILES CSc1c(C)onc1NS(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=PRTUPPORJRVRBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091534   

TargetEndothelin-1 receptor(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091534(4-tert-Butyl-N-(5-methyl-4-methylsulfanyl-isoxazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50091534(4-tert-Butyl-N-(5-methyl-4-methylsulfanyl-isoxazol...)
Affinity DataIC50:  3.50E+4nMAssay Description:Binding affinity towards displacement of [125 I] ET-3 from COS-7 cells transfected with porcine Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed