BDBM50091624 7-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL324940

SMILES O=C1COc2cc(ccc2N1)C#CCCN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=NMTXQGIIEZHTFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091624   

TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091624(7-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-4H-benz...)
Affinity DataIC50:  1.10E+3nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091624(7-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-4H-benz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091624(7-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-4H-benz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed