BDBM50092543 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl ester::CHEMBL121913
SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ncccn1
InChI Key InChIKey=QZWGOZASIAHHGS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50092543
Affinity DataKi: 1nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]-GR-113,...More data for this Ligand-Target Pair
Affinity DataKi: 2.47nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4C receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4A receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.03nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4D receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.10nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4B receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Concentration required to produce half-maximal response against 5-hydroxytryptamine receptor on the L-type calcium current (I Ca) in isolated human a...More data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:,Antagonism of stimulation of 5-hydroxytryptamine receptor on the L-type calcium current (I Ca) in isolated human atrial myocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Concentration required to produce half-maximal response against 5-hydroxytryptamine receptor in the presence of 10 nM compound in isolated human atri...More data for this Ligand-Target Pair