BDBM50092770 CHEMBL3586398

SMILES CO[C@H]1CC[C@H](CN2CC(=O)Nc3ncc(nc23)-c2ccc(nc2)C(C)(C)O)CC1

InChI Key InChIKey=YDXFZRXCBRFBQS-IAGOWNOFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092770   

LigandPNGBDBM50092770(CHEMBL3586398)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092770(CHEMBL3586398)
Affinity DataIC50:  170nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092770(CHEMBL3586398)
Affinity DataIC50:  230nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed