BDBM50092773 CHEMBL3586394

SMILES CC(C)(O)c1ccc(cn1)-c1cnc2NCC(=O)N(CC3CCOCC3)c2n1

InChI Key InChIKey=HDJQPSZZAWLLJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092773   

LigandPNGBDBM50092773(CHEMBL3586394)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092773(CHEMBL3586394)
Affinity DataIC50:  46nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092773(CHEMBL3586394)
Affinity DataIC50:  200nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed