BDBM50092782 CHEMBL3586387

SMILES Cc1nc(ccc1-c1cnc2NCC(=O)N(CCC3CCOCC3)c2n1)-c1nc[nH]n1

InChI Key InChIKey=VLSSMLSPCKXABU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092782   

LigandPNGBDBM50092782(CHEMBL3586387)
Affinity DataIC50:  510nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092782(CHEMBL3586387)
Affinity DataIC50:  8nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092782(CHEMBL3586387)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50092782(CHEMBL3586387)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed