BDBM50092998 CHEMBL72786::Derivative of Natrindole

SMILES CCCCC(=N)NCc1ccc2[nH]c3C4Oc5c6c(CC7N(CC8CC8)CCC46[C@@]7(O)Cc3c2c1)ccc5O

InChI Key InChIKey=LHABVQRHEYQPMS-FHLQZRSLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092998   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50092998(CHEMBL72786 | Derivative of Natrindole)
Affinity DataKi:  0.0610nMAssay Description:Compound was evaluated for its binding affinity to CHO cells expressing cloned human Opioid receptor kappa 1 by displacing [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50092998(CHEMBL72786 | Derivative of Natrindole)
Affinity DataKi:  3.5nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor mu 1 of guinea pig brain membrane by displacing [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50092998(CHEMBL72786 | Derivative of Natrindole)
Affinity DataKi:  5.5nMAssay Description:Compound was evaluated for its binding affinity to CHO cells expressing cloned human Opioid receptor delta 1 by displacement of [3H]-Cl-DPDPEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed