BDBM50093132 CHEMBL75749::[3-(4-Guanidino-benzyl)-ureido]-acetic acid 5-{2-[3-(4-guanidino-benzyl)-ureido]-acetoxy}-cyclooctyl ester

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#8]-[#6@H]-2-[#6]-[#6]-[#6]-[#6@H](-[#6]-[#6]-[#6]-2)-[#8]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#7]-[#6]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cc1

InChI Key InChIKey=GFCDSLGQAHTBKQ-PSWAGMNNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093132   

TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093132(CHEMBL75749 | [3-(4-Guanidino-benzyl)-ureido]-acet...)
Affinity DataKi:  2nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093132(CHEMBL75749 | [3-(4-Guanidino-benzyl)-ureido]-acet...)
Affinity DataKi:  7.80E+4nMAssay Description:Inhibitory potency against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093132(CHEMBL75749 | [3-(4-Guanidino-benzyl)-ureido]-acet...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093132(CHEMBL75749 | [3-(4-Guanidino-benzyl)-ureido]-acet...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed