BDBM50093716 (6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfanylmethyl)-7-[2-(4-hydroxy-phenyl)-acetylamino]-7-methoxy-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-methyl-benzyl ester::CHEMBL78373

SMILES CO[C@]1(NC(=O)Cc2ccc(O)cc2)[C@H]2OCC(CSc3nnnn3CC(O)=O)=C(N2C1=O)C(=O)OCc1cccc(C)c1

InChI Key InChIKey=OMVKDWDUCSMCMK-IAPPQJPRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093716   

TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093716((6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfany...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093716((6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfany...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093716((6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfany...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed