BDBM50093734 (6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-methoxy-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-methyl-benzyl ester::(6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-methoxy-3-(1-methyl-2,3-dihydro-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-methyl-benzyl ester::CHEMBL76624

SMILES CO[C@]1(NC(=O)Cc2ccc(O)cc2)[C@H]2OCC(CSc3nnnn3C)=C(N2C1=O)C(=O)OCc1cccc(C)c1

InChI Key InChIKey=GQEMMHIPZFYRTP-VPUSJEBWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093734   

TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093734((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093734((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed