BDBM50093797 Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl)-ethyl]-pyrrolidin-3-yl}-amide::CHEMBL84240

SMILES O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=CUOGJNWOVCPXJN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093797   

TargetSerotonin 2 (5-HT2) receptor(RAT)
Welfide

Curated by ChEMBL
LigandPNGBDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Welfide

Curated by ChEMBL
LigandPNGBDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataKi:  110nMAssay Description:Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Welfide

Curated by ChEMBL
LigandPNGBDBM50093797(Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:The compound was evaluated for the ability to displace [3H]- 8-OH -DPAT from 5-hydroxytryptamine 1A receptor ( striata of male wistar rats)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed