BDBM50094298 CHEMBL16117::N-[(S)-1-{3-[4-(3-Amino-propylamino)-butylamino]-propylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-butyramide::N-[1-{3-[4-(3-Amino-propylamino)-butylamino]-propylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-butyramide::Philanthotoxin-343
SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCNCCCCNCCCN
InChI Key InChIKey=DTWANULJDRVTFI-NRFANRHFSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50094298
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit delta(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Antagonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.18E+4nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.67E+4nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced currentMore data for this Ligand-Target Pair