BDBM50094987 5-Hydroxy Rofecoxib::5-Hydroxy-4-(4-methanesulfonyl-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL1084

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1O)c1ccccc1

InChI Key InChIKey=NCBVUSNBLYMFPP-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094987   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1O)c1ccccc1
Show InChI InChI=1S/C17H14O5S/c1-23(20,21)13-9-7-12(8-10-13)15-14(16(18)22-17(15)19)11-5-3-2-4-6-11/h2-10,17,19H,1H3
Affinity DataIC50: 8.70E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1O)c1ccccc1
Show InChI InChI=1S/C17H14O5S/c1-23(20,21)13-9-7-12(8-10-13)15-14(16(18)22-17(15)19)11-5-3-2-4-6-11/h2-10,17,19H,1H3
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair