BDBM50095149 CHEMBL3589536

SMILES OC(=O)CCC(=O)Nc1nc2CC[C@@H](Cc2s1)NC(=O)c1cc(Br)c(Br)[nH]1

InChI Key InChIKey=XMGKNMJESPOXJS-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095149   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095149(CHEMBL3589536)
Affinity DataIC50:  49nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluorescence based DNA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095149(CHEMBL3589536)
Affinity DataKd:  10nMAssay Description:Binding affinity to Escherichia coli DNA gyrase subunit B N-terminal 24 kDa domain by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095149(CHEMBL3589536)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095149(CHEMBL3589536)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed