BDBM50095310 CHEMBL3589894
SMILES CNC(=O)c1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
InChI Key InChIKey=HPIUHDCRVYDAEJ-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50095310
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.2 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.3 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Nav1.7 expressed in SHSY5Y cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human Nav1.2 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by IonWorks Quattro selectivity assayMore data for this Ligand-Target Pair